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K (Patlak Ref): Patlak Reference Plot for FDOPA

The K (Patlak Ref) model is exactly the same model as the standard Patlak model, except that the blood activity is replaced by the activity of a reference TAC devoid of trapping [29]:

PXMOD Patlak Reference Equation

In this situation the slope K of the plot equals

Equation Patlak Reference

with an equilibrium constant Keq.

This model is often used to calculate an index Kocc of the FDOPA influx using an occipital TAC as the reference [30].