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List of Implemented Models

The following lists provides a quick overview of the implemented models. If one of the models does not appear in the Model list of the Menu it may have been hidden and can be added using the configuration facility.

Note that outdated models from previous versions have a "Legacy" in the name. These models are only supported for backward compatibility.

Models with Blood Data

Model Name

Data

Dynamic?

Blood?

Vt (3 Calc Methods)

Tracers without irreversible uptake.

yes

yes

Vt (Logan Plot)

Tracers without irreversible uptake.

yes

yes

Vt (RE-GP Analysis, Zhou)

Tracers without irreversible uptake

yes

yes

1-Tissue (Alpert)

Tracers which allow time-weighted integral solution.

yes

yes

1-Tissue (Wu GRRSC)

Tracers with 1-tissue compartment kinetics

yes

yes

2-Tissue Compartments, K1/k2

Tracer with 2-tissue compartment kinetics; preferably with K1/k2 constant and k4=0.

yes

yes

2-Tissue K1/k2, RR

Tracer with 2-tissue compartment kinetics. Fit with Ridge-Regression

yes

yes

Receptor Reference Models

Model Name

Data

Dynamic?

Blood?

BPnd (6 Calc. Methods)

Reversible receptor tracers

yes

no

BPnd (Ichise MRTM0 Ref)

123I IBF, 11C Raclopride

yes

no

BPnd (Ichise MRTM Ref)

11C DASB

yes

no

BPnd (Ichise MRTM2 Ref)

11C DASB

yes

no

BPnd (Logan Ref)

11C Raclopride, 11C dMP

yes

no

BPnd (Gunn SRTM Ref)

11C Raclopride, 11C CH 23390, 11C CTF

yes

no

BPnd (Wu SRTM2 Ref)

11C Raclopride, 11C Flumazenil, 18F FCWAY

yes

no

K (Patlak Ref)

FDOPA or another irreversibly binding tracer with a suitable non-trapping reference

yes

no

MP4A (Nagatsuka RLS Ref)

11C-MP4A, acetylcholine analog

yes

no

Brain Glucose Consumption

Model Name

Data

Dynamic?

Blood?

MRGlu (FDG Patlak)

18FDG-PET

yes

yes

MRGlu (FDG Autorad)

18FDG-PET

yes

yes

C14 Autoradiography

14C labeled glucose, autoradiographic cuts

no

yes

C14 Autoradiography;
Glucose variable

14C labeled glucose, autoradiographic cuts

no

yes

Brain Perfusion and Blood Volume

Model Name

Data

Dynamic?

Blood?

rCBF (Alpert)

H215O-PET

yes

yes

rCBF (Watabe Ref)

H215O-PET

yes

no

rCBF (Autorad)

H215O-PET

no

yes

rBV (Autorad)

11CO-PET

no

yes

Miscellaneous Models

Model Name

Data

Dynamic?

Blood?

Factor Analysis (2 TACs)

Any dynamic data set.

yes

no

Factor Analysis (H2O, Lung TAC)

Myocardial H215O-PET.

yes

no

z-Score

Any static Volume Data

no

no

Correlation

Any dynamic Volume Data

yes

no

Regression

Any dynamic Volume Data

yes

no

Fourier Analysis

Any dynamic Volume Data

yes

no

Fractal Dimension

Any dynamic Volume Data

yes

no

Note that the partial volume correction is not any longer supported because a better solution has become a part of the PMOD Base functionality.