Mouse Brain Template

For the analysis of mouse brain data the VOI template Mouse (M.Mirrione) [1,2] is available. The species used were C57BL/6J mice. We would like to thank Martine Mirrione for providing the data and helping with the integrations.

Spatial Normalization

Two normalization templates are available in the fusion tool as entries in Menu/File/Load User Template:

• Mouse (M.Mirrione)-FDG: This is an FDG baseline PET template as illustrated below.
• Mouse (M.Mirrione)-T2: This is a T₂-weighted MRI PET template which is in the same space as the PET templates.

The images of these templates can be found in the resources/templates/usertemplates directory.

VOI Template

The VOI template Mouse (M.Mirrione) can be selected in the list of included template VOIs. The corresponding files can be found in the resources/templates/voitemplates/Mouse (M.Mirrione) directory.

References

[1] Ma Y, Hof PR, Grant SC, Blackband SJ, Bennett R, Slatest L, McGuigan MD, Benveniste H. A three-dimensional digital atlas database of the adult C57BL/6J mouse brain by magnetic resonance microscopy. Neuroscience. 2005;135(4):1203-15.

2. Mirrione MM, Schiffer WK, Fowler JS, Alexoff DL, Dewey SL, Tsirka SE. A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator. Neuroimage. 2007;38(1):34-42.